Molecule to Corporation

Faculty:  Steve Verhey
Telephone:  x6009
e-mail: verhey@evergreen.edu
Office Hours:  Fridays, 1:00 - 2:30/by appointment

About this web page
Preliminary program description/schedule
Book list

Week Links: 1-2-3-4-5-6-7-8-9-10-Eval-Bottom

Fine print:  all events are tentative until they have occurred
DON"T PRINT THIS YET!  New items added regularly
Week 1 -- Chemistry Background

Mon., 29 Mar 1999 Tues., 30 Mar 1999 Wed., 31 Mar 1999 Thurs., 1 Apr 1999 Fri., 2 Apr 1999
Lecture 0 -- Introductions and overview

Lab I, 1037
9 - 10 am
 


Lecture 1 --  Atomic anatomy & covalent bonding

Lab I, 3033
9 - 10 am

Reading:  Purves, pp 19-24

EXTRA! The Periodic Table
 


Lecture 2 -- bonding, water, functional groups

LH 4
9 - 10 am

Reading:  Purves, pp 24-40


Lecture 3 -- macromolecules and monomers

LH 4
9 - 10 am

Reading:  Purves, pp 41-63

Library Workshop
Library 2218
9 - 10 am
 
Seminar I
Lab I, 3033
10:30 - 12

Read and be prepared to discuss:  Covenant

Print, read, and bring to class:  Informal Fallacies
 

CAL
Lab II, 1223
10 - 12:30 

Molecular Models


Seminar II
Lab I, 1051

Reading:  Rifkin, pp ix-115

Possibly useful:  How to Read a Nonfiction Book

No Lab Today    
Lab Today!
Lab I, 2040
1 - 3

Lab Overview
 

Week 2 -- Pathways & Proteins
Monday, 5 Apr 1999 Tuesday, 6 Apr 1999 Wednesday, 7 Apr 1999 Thursday, 8 Apr 1999 Friday, 9 Apr 1999
Lab A
Lab I, 2046

Isolation of Mitochondria

All day today! (9-5+)


Lecture 4 -- Metabolic Regulation

Lab I, 3033
9 - 10 am

Reading:  Dennis, Ch. 5
 

Lecture 5 -- Protein Structure

LH 4
9 - 10 am

Reading:  Purves, pp 51-57

Protein structure workshop

Lab B
Lab I, 2046

Isolation of Mitochondria

All day today! (9-5+)

Library Workshop
Library 2218
9 - 10 am
Lab A
Lab I, 2046

All day today! (9-5+)

Seminar I
Lab I, 3033
10:30 - 12

Discussion topics

Corporate Analysis

Lib 2219
10:30-12 


Lab B
Lab I, 2046

All day today! (9-5+)
 

Lab A
Lab I, 2046

All day today! (9-5+)

   
Lab B
Lab I, 2046

All day today! (9-5+)
 

Week 3 -- Gene Regulation & The "Terminator" Gene
Mon., 12 Apr 1999 Tues., 13 Apr 1999 Wed., 14 Apr 1999 Thurs., 15 Apr 1999 Fri., 16 Apr 1999
CAL 
9 - 10:30

Introduction to Rasmol

Rasmol homepage

Rasmol Tutorial

EXTRA!  Simulated motion of an alpha helix!


Lecture 7  -- Gene Regulation I

Lab I, 3033
9 - 10 am

Bring to class:  both biochemical pathways charts!

Reading this week:  Purves Ch 9, 11-12, 14; Dennis Ch 1-2


Lecture 8 -- Gene Regulation II

LH 4
9 - 10 am


Field Trip to OSU to see  Paul Talalay, the Johnny Appleseed of Broccoli!

Sponsored by the Linus Pauling Institute.

Return from field trip
  Seminar I
Lab I, 3033
10:30 - 12

Reading: rest of Rifkin, except Ch. 4
 


Corporate Analysis -- Biotech companies

Lib 2219
10:30-12 

Lab A
Lab I, 2046
1-5 pm

Isolation of mtDNA
 

   
Week 4 -- Photosynthesis I
Mon., 19 Apr 1999 Tues., 20 Apr 1999 Wed., 21 Apr 1999 Thurs., 22 Apr 1999 Fri., 23 Apr 1999

Library Workshop
Lab I, 1037
9 - 10 am

Lecture 10 -- Gene Regulation:  Biotechnological applications

Lab I, 3033
9 - 10 am

EXTRA!  How the Terminator Terminates!

RAFI's Terminator Page!

US Patent 5,723,765!
 


Lecture 11 -- Plastids, pigment, & light

LH 4
9 - 10 am

Reading Weeks 4 & 5: Purves Ch. 8; Dennis Ch 17, 19-23


Lecture 12 -- Pigment, light, antioxidants, LHC

LH 4
9 - 10 am

Corporate Analysis -- company reports

Library 2218
9 - 10 am

Corporate Web Sites

  Seminar I
Lab I, 3033
10:30 - 12

Discussion:  Field trip, writing & writing assignments.

Reading: Notes from Field trip
 

CAL
Lab II, 1223
10:30 - 12 noon

DNA binding domains

Downloading molecules

The Amino Acid Viewer!


Seminar II
Lab I, 1051

Reading: Kloppenburg, Preface - Ch. 6

Lab A
Lab I, 2046
1-5 pm

Library Construction I

EXTRA!  Paul Talalay's patents!

US Patent 5,725,895
US Patent 5,411,986

US Patent & Trademark Office Home Page!

 
Lab B
Lab I, 2046
1-5 pm

Library Construction I

Week 5 -- Photosynthesis II
Mon., 26 Apr 1999 Tues., 27 Apr 1999 Wed., 28 Apr 1999 Thurs., 29 Apr 1999 Fri., 30 Apr 1999

Corporate Analysis -- Factors affecting stock price

Lab I, 1037
9 - 10 am


Lecture 13 -- Light reactions concluded, dark reactions begun

Bring biochemical pathways charts!

Lab I, 3033
9 - 10 am

Reading Weeks 4 & 5: Purves Ch. 8; Dennis Ch 17, 19-23


Lecture 14 -- Photosynthesis:  Science 284:654-657

LH 4
9 - 10 am


Lecture 15 -- Photosynthesis: Dark Reactions

LH 4
9 - 10 am

Informal Library Workshop
  Seminar I
Lab I, 3033
10:30 - 12

Conclude company reports, continue with photosynthesis

CAL
Lab II, 1223
10:30 - 12 noon

Lycos Money Guide

The Motley Fool

PSII in the movies!

The movie explained!

Photosynthesis proteins


Seminar II
Lab I, 1051

Reading: Kloppenburg, Ch. 6 - Ch. 10

Lab 
Lab I, 2046
1-5 pm

Group A:  Library Construction II

   
Lab B
Lab I, 2046
1-5 pm

Everyone meets for lab today!

Group A:  Bacterial Transformation

Group B:Library Construction II

Week 6 -- N Metabolism
Mon., 3 May 1999 Tues., 4 May 1999 Wed., 5 May 1999 Thurs., 6 May 1999 Fri., 7 May 1999

Corporate Analysis
Lab I, 1037
9 - 10 am

Lecture 16 -- Photosynthesis Biotechnology

Lab I, 3033
9 - 10 am

Reading this week: Dennis Ch 29-31


Lecture 17 -- Nitrogen metabolism

LH 4
9 - 10 am

Bring biochemical pathways charts!


Lecture 18 -- Nitrogen Fixation

LH 4
9 - 10 am

EXTRA! Nitrogen fixation web page!


 

Informal Library Workshop

  Seminar I
Lab I, 3033
10:30 - 12

Work on papers independently


CAL
Lab II, 1223
10:30 - 12 noon

RUBISCO structures

EXTRA!  The Periodic Table of Poetry!
 


Seminar II
Lab I, 1051

Reading: Avery, Ch. 1 - 12 

EXTRA!  Ames & Gold: US Senate Testimony on Cancer & Carcinogens!

The Hudson Institute! (surf to Policy Centers, then Center for Global Food Issues)
Lab A
Lab I, 2046
1-5 pm

Everyone meets for lab today!

Group A:  Isolate/analyze Plasmid DNA

Group B:  Bacterial Transformation

   
Lab B
Lab I, 2046
1-5 pm

Isolate/analyze Plasmid DNA

Week 7 -- Fatty Acid Metabolism & Other Products
Mon., 10 May 1999 Tues., 11 May 1999 Wed., 12 May 1999 Thurs., 13 May 1999 Fri., 14 May 1999

Special Guest:  Chris Mundt, OSU Professor of Plant Pathology, on debating Dennis Avery

Lab I, 1037
9 - 10 am


Lecture 19 -- Amino Acid Metabolism

Lab I, 3033
9 - 10 am

Reading this week: Dennis Ch 26-27


Lecture 20 -- Fatty Acid Metabolism

LH 4
9 - 10 am


Lecture 21
LH 4
9 - 10 am

No lecture today!

Library Workshop
Library 2218
9 - 10 am

No library workshop today!

  Seminar I
Lab I, 3033
10:30 - 12

Reading: Avery, Ch. 13 - Epilogue

CAL
Lab II, 1223
10:30 - 12 noon

Seminar II
Lab I, 1051

No seminar today!

Lab A
Lab I, 2046
1-5 pm

Everyone meets for lab today!

Groups A & B:  DNA Sequencing Reactions
 

   
Lab B
Lab I, 2046
1-5 pm

No lab today!
 

Week 8 -- Pesticides & Pesticide Resistance
Mon., 17 May 1999 Tues., 18 May 1999 Wed., 19 May 1999 Thurs., 20 May 1999 Fri., 21 May 1999

Corporate Analysis -- Monsanto & Seed Company Aquisition Debt

CAL
9 - 10 am

Monsanto on NPR


Lecture 22 -- Pesticides & Herbicide Resistance I

Lab I, 3033
9 - 10 am

Reading this week: Dennis Ch 28


Field trip to "Biodevastation 3" agricultural biotechnology conference.

Lecture 24 -- Herbicides & Herbicide Resistance II

LH 4
9 - 10 am

Informal Library Workshop
Biotech Issues Papers Due Today!
Seminar I
Lab I, 3033
10:30 - 12

Field trip preparation discussion

EXTRA! A not necessarily objective look at investing in Monsanto!

EXTRA!  NPR Audio:  Monarchs & Biotechnology!
Seminar II
Lab I, 1051

Biodevastation 3 Debrief


Lab A
Lab I, 2046
1-5 pm
EXTRA! EXTOXNET Pesticide Database!   Lab B
Lab I, 2046
1-5 pm
Week 9 -- Plant Genetic Engineering
Mon., 24 May 1999 Tues., 25 May 1999 Wed., 26 May 1999 Thurs., 27 May 1999 Fri., 28 May 1999

Corporate Analysis
Lab I, 1037
9 - 10 am

Lecture 25 -- Herbicides & Herbicide Resistance Concluded

Lab I, 3033
9 - 10 am

Reading this week: Dennis Ch 35, 37


Lecture 26 -- Plant Transformation Systems

LH 4
9 - 10 am


Lecture 27 -- Issues in Genome-Scale Sequencing

LH 4
9 - 10 am

Special Guest:

Nan Newell, founding CEO and Chairman of the Board, Naiad Technologies

Library 2218
10-11 am
 

Seminar I
Lab I, 3033
10:30 - 12

Reading: Biopiracy Articles

CAL
Lab II, 1223
10:30 - 12 noon

Analyze Sequence Results!


Seminar II
Lab I, 1051

Reading: Djerassi (all)

EXTRA:  www.djerassi.com!

Lab A
Lab I, 2046
1-5 pm
   
Lab B
Lab I, 2046
1-5 pm
Week 10 -- Loose Ends
Mon., 31 May 1999 Tues., 1 June 1999 Wed., 2 June 1999 Thurs., 3 June 1999 Fri., 4 June 1999
Campus Holiday:  Memorial Day
ALL DAY:

Tour UW Genome Center (confirmed) and Botanical Conservatory

Lecture 29 -- Systemic Acquired Resistance

LH 4
9 - 10 am

Lecture 30 -- Molecule to Corporation Conclusion

LH 4
9 - 10 am

Oral Exam Meetings
  ALL DAY:

Tour UW Genome Center (confirmed) and Botanical Conservatory

CAL
Lab II, 1223
10:30 - 12 noon

Special presentation:  "Salmonid Stock Identification using Microsatellite 
Markers" -- Tiffany Mullins

Seminar II
Lab I, 1051

Reading: Biopiracy Articles

Oral Exam Meetings
  ALL DAY:

Tour UW Genome Center (confirmed) and Botanical Conservatory

  Oral Exam Meetings Oral Exam Meetings
Evaluation Week
Mon., 7 June 1999 Tues., 8 June 1999 Wed., 9 June 1999 Thurs., 10 June 1999 Fri., 11 June 1999
Random Fun Links

Current Precipitation Situation

Does anybody really know what time it is?  The US Naval Observatory does!

Journal of Plant Growth Substances's Instructions for Authors!


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Madeby: Steve Verhey
E-mail:verhey@evergreen.edu
Last modified: 17Mar99